Registered Charity No. 1044906 01691 404661

ORTHOPAEDIC
INSTITUTE
RESEARCH

Spinal Studies

Spinal Studies Research Group

The team has continued its work on identifying potential biomarkers in the bloods of patients following a spinal cord injury (SCI) to assist predicting clinical outcome. A paper from the group looking at routine bloods from a relatively small group of SCI patients has recently been accepted for publication in the Journal of Neurotrauma. Although this is great news, the team is now focussing its efforts on a much larger group of patients (>500) in addition to continuing its work on specific neurological markers that can also be assessed from blood samples. It is hoped that these biomarkers will be able to not only enhance the prediction of the patient’s neurological outcome but direct current treatments and rehabilitation regimes so that patients achieve their best clinical outcome.

Spinal Studies Projects

BIOMARKER DISCOVERY AND USE IN SPINAL CORD INJURY PATIENTS: IDENTIFYING NEW TREATMENT TARGETS AND MARKERS FOR PREDICTING CLINICAL OUTCOME

Mateus Bernardo Harrington, Sharon Owen, Charlotte Hulme, Heidi Fuller, Naveen Kumar, Joy Chowdhury, Aheed Osman, Srinivasa Budithi, Paul Cool and Karina Wright

Funded by the Orthopaedic Institute and the Midland Centre for Spinal Injuries (MCSI), Oswestry

Pulsed Magnetic Stimulation-Managing Spasticity in Spinal Cord Injury (OsStim)

Andrew Roberts (Chief Investigator), Sarah Turner, Aheed Osman, Naveen Kumar, Joy Chowdhury, Jan Herman Kuiper, Anand Pandyan, Jayne Edwards, Lisa Burgess-Collins

Funded by the Orthopaedic Institute

Developing a Cell Therapy delivery system for Chronic Wounds

Angus Armstrong Twigg, Mateus Bernardo Harrington, Naveen Kumar, Joy Chowdhury, Aheed Osman, Srinivasa Budithi and Karina Wright

Funded by Orthopaedic Institute

Are Primary Cilia involved in degeneration of the Intervertebral Disc?

Sharon Owen, Sue McGlashan*, Sarfraz Ahmad, Birender Balain, Shashank Chitgopkar, Neil Davidson, Sujay Dheerendra, Sudarshan Munigangaiah, Matthew Ockendon, Jayesh Trivedi and Sally Roberts *University of Auckland, New Zealand

Funded by the Orthopaedic Institute and Institute of Liberal Arts and Sciences, Keele University